Brad Anderson's interest in cartooning dates back to his early childhood. He drew popular cartoon characters and sold his first cartoons to an aviation magazine while still in high school. Anderson continued his art career as a freelancer while serving four years in the U.S. Navy during World War II. He then attended Syracuse University's School of Fine Arts.
Upon graduation from Syracuse, Anderson moved into advertising where he continued to freelance. In 1953 Anderson decided to concentrate on his cartooning full-time. A year later he created Marmaduke, the funny strip about a big Danish dog, which was released in newspapers in November 1954. Currently 'Marmaduke' appears in more than 500 newspapers around the world.