Carlos Clemen began his career in 1931, drawing for publications like El Purrete, Pololo, Mustafá and Barrilete, for which he created among others the series 'Barrilete y los Suyos', 'Don Cirilo Blanco' and 'Las Graciosas Aventures de Chiquín'. In 1933 he began working on serials, such as 'El Mundo Perdido' and 'La Isla Misterioso' for Figuritas. These were followed by 'Carpincho' and 'Las Aventuras de Pepe Bujía'.
Clemen was also the publisher of his own comic books, such as Corso Pete, Trinchera and Filmograf. With writer A. J. Grassi he began what is considered the first Argentine science-fiction series, 'Robert Ax, Médico del Siglo XXX' (1954). For Corso Pete, he drew 'Torpedos Humanos, which was later continued by Walter Casadei. One of his final comic stories was 'Barracuda', which he made under the pseudonym Paul Corydon for the Uruguayan magazine Bandera Negra in 1959. His brothers José and Juan were also comic artists.