Maurice Cuvillier started out working as an illustrator for Le Pêle-Mêle, L'Almanach Vermot, Les Petits Bonshommes, Parisiana and Le Dimanche Illustré during the late 1910's and throughout the 1920's. He did his first comics work for Lisette (1929), Guignol (1931), L'Épatant (1931-38) and Pierrot. He became best known for his children's comics, starting with 'Zimbo et Zimba', published by Editions Croisade des Enfants in 1937.
He created his most famous characters for the publishing house Fleurus during the 1940's. His series 'Perlin et Pinpin' first appeared in Âmes Vaillantes' in September 1940.
In the following year, he created 'Sylvain et Sylvette', a series about a brother and sister who get lost in a forest, published in Coeurs Vaillants and in a series of albums. Cuvillier created a complete cast of talking animals around the characters, which made the comic one of France's most popular animal series.
During the 1940s, he was also a present in Pat magazine (presumably reprints). In 1956 Maurice Cuvillier got ill and had to leave 'Sylvain et Sylvette' to Jean-Louis Pesch and Claude Dubois, and died a year later.