After his studies at the scientific grammar school, Pasquale Del Vecchio went to study architecture in Milan. While studying, he made his comics debut in the magazine 1984. Later on, he joined Bonelli publishers, where he started out drawing for Zona X. He became one of the main artist of the series 'Nick Raider'. He has also illustrated 'Napoleone'. In 2004, he began the series 'Russell Chase' with scriptwriter Richard D. Nolane at the French publisher Les Humanoïdes Associés'.