Rob Derks studied to be a drawing teacher, which led him to decide to become a comic artist. His first comics were printed in the magazines De Stripper and Diogenes. One of his early comics creations was 'AbsolutLee', a comic based on singer Lee Towers.
His comic 'Pakje Bakmeel', about a box of baking flour, was published every week in the newspaper Metro for several years. Rob Derks self-published 'Pakje Bakmeel Presenteert' (1998), 'Pakje Bakmeel Bakt er Wel Wat Van' (2000) and 'Pakje Bakmeel 1& 2' (2005 & 2006).
'Pakje Bakmeel' is now published in Roetsj, a Dutch children's magazine. He also participates in the 'Fred van Honderloo' book project with actor Joris Lutz, and he makes illustrations for Band Zonder Banaan, Firma Verbaal and the website www.nuwijweer.nl. For Zone 5300 he makes portraits of musicians for the Rob & Roll Hall of Fame.
He is also known for his large crowded drawings, in the tradition of Jan van Haasteren, that he makes for publisher Kluitman. Rob Derks is a member of Studio Noodweer, together with René Leisink, Jan Dirk Barreveld and Michiel van de Vijver.