Reuben Lucius Goldberg studied at the University of California at Berkeley. After graduating in 1904, he started out working as an engineer, designing sewers for the city of San Francisco. Six months later, he started working as a sports cartoonist for the San Francisco Chronicle. In 1907 he moved to New York after selling his Sunday half-page strip 'Mike and Ike'. This comic didn't generate much response. With a lot of effort, Rube Goldberg eventually landed a job at the New York Evening Mail, where he created the 'Foolish Questions' panel. Apart from drawing comics, he also took a shot at vaudeville, becoming a stand-up comedian and fortune-teller in 1911.
Between 1907 and 1915, Rube Goldberg's large output included 'The Candy Kid', 'Lunatics I have Met', 'Soup and Fish', 'I'm the Guy', 'They All Look Good When You're Far Away' and 'The Weekly Meeting of the Tuesday Ladies' Club'. Goldberg's sports cartoons kept growing in popularity, and in 1915 he was assigned by to create a Sunday strip which was called 'Boob McNutt'. After that he re-launched his 'Mike and Ike' characters, this time with success. 'Boob McNutt', a helpless clown, was syndicated by McNaught until 1934.
In addition, he launched new strips for the Hearst papers, such as 'Phoney Films', 'Boobs Abroad' and 'Life's Little Jokes'. 'The Inventions of Professor Lucifer Gorgonzola Butts' resulted from Goldberg's engineering background, and was the artist's one-man war against modern gadgetry. His many creations of intricate and absurd inventions were hilarious and a "Rube Goldberg" contraption became part of American popular vocabulary. In 1928, Goldberg started his first (and probably best) daily strip, 'Bobo Baxter', which ran until 1930. In 1934 he created 'Doc Wright', about a doctor and his patients. In 1936 'Lala Palooza' was launched, but was not successful - and it ended in 1939.
Rube Goldberg was at his best and wackiest when he made his miscellany pages, such as 'Rube Goldberg's Sideshow', his last strip effort in 1939. He then focused on his editorial cartoons, which won him a Pulitzer Prize. He was additionally an essayist, poet, and playwright. In 1945 he co-founded the National Cartoonists' Society, becoming its first president. The prestigious "Rueben Awards" were named after him. At the age of 80, Goldberg embarked on a new career as a sculptor. Rube Goldberg died in 1970.