Gérard Lauzier studied architecture and philosophy before he started his artistic education at the ateliers of Perret and Lagneaux. After producing some work in the press, he went to Brazil for a couple of years, where he did advertising work, as well as caricatures for Le Journal de Bahia (1958-59). Back in France, he took on humorous illustrations again. Until 1973, he contributed to several magazines, including Lui, France-Soir, Paris-Match and Paris-Presse.

In 1974, he entered the comics field, producing the albums 'Lili Fatale' and 'Un Certain Malaise'. In that same year, he made 'Tranches de Vie' for Pilote and 'Zizi Panpan' for Lui. A year later he created 'Les Chroniques de l'île Grande', directly inspired by his trip to Brazil.

In 1976, Lauzier wrote the western parody 'Al Crane' for Alexis, and in the following years, he made 'La Course du Rat' (1978), 'La Tête dans le Sac' (1980), 'Les Cadres' (1981) and 'Souvenirs d'un Jeune Homme' (1982). He then dropped his comics activities to concentrate on theatre and cinema scriptwriting. He cooperated on several theatrical productions, among others an adaptation of his comic 'Tranches de Vie'. In 1992, he returned to comics with 'Portrait de l'Artiste'.