Mark Lewis has had comics work published by Fantagraphics, Express Publications and Paradox Press. With writer Nat Gertler, he co-created 'Mister U.S.', which appeared in Big Bang Comics. His own creation 'Bugboy' was published as a one-shot by Image Comics.
Lewis has been a major contributor to Big Bang, designing most of their logos and helping to design many of the characters, including 'The Badge and his Rookies', which he illustrated in a 1940s Simon & Kirby style. In addition, Mark drew dozens of faux covers in a variety of ghosted art styles for the 'History of Big Bang Comics' issues. He also contributed to Parody Press's 'Adolescent Radioactive Black Belt Hamsters' in the early 1990s.