Bill Perry was born in Chicago in 1905. He began his career as a shipping clerk for the Chicago Tribune Syndicate, and took art classes in the evenings. He was hired as an assistant on 'Harold Teen' by Carl Ed, and started assisting Frank King on 'Gasoline Alley' in 1925. In 1945, Bill Perry came up with his own Sunday page comic, 'Ned Handy'. He took over the 'Gasoline Alley' Sunday page in 1951 and continued it until 1975.