Sergio Salma was born in Charleroi in 1960 as the son of Italian parents. After an artistic education at the Academy of Fine Arts in Mons, he made his first album at Michel Deligne: 'Faits Divers' with a script by Francesco Pittau in 1983. Then, he created the 'Marcobello' series in À Suivre and worked on several magazines for children. For the magazine Spirou, he created such series as 'Isaline et Jean-Luc' (art by Alec Séverin), 'Suzy' (art by Carine De Brab), 'Attention École' (art by Curd Ridel) and 'Petit Rigolo Illustré' (art by several artist, as well as Salma himself).
In 1989, he started the juvenile 'Nathalie' series in Tintin Reporter at Casterman publishers. A year later, he "gave birth" to a second heroine, 'Mademoiselle Louise', in cooperation with André Geerts. While still working on 'Nathalie', Salma began the humorous 'Surimi' series for a more adult public. In addition, he took on 'Ice Fred' in the periodical P'tit Loup.