Frank Smith worked in animation during the 1950s and 1960s. He cooperated on among others 'Mr Magoo, 'Gerald McBoing Boing' and 'A Boy Named Charlie Brown'. He began working for the comic department of the Disney Studios in the 1970s. Between 1973 and 1976, he drew 'Donald Duck' stories for foreign Disney publications. He took over the 'Donald Duck' newspaper strip from Frank Grundeen in 1976, and continued it until 1986. He also did a newspaper strip based on W.C. Fields between 1982 and 1986, and art on Hanna-Barbera comic books like 'Laff-a-Lympics' and 'Great Grape Ape' in 1978-1979.