Joe Staton began his career at Charlton Comics in 1971, where his most notable work was the creation of 'E-Man' with Nicola Cuti in 1973. His art was also present in 1970s Marvel and Warren titles (he inked Sal Buscema's 'Hulk' stories), but he is best known for his work for DC Comics. He was initially hired to work on the revival of 'Justice League of America' in All Star Comics, but he also did spin-offs starring 'Power Girl' and 'The Huntress'.
He subsequently had runs on 'Superboy and the Legion of Super-Heroes' and 'Green Lantern', the latter with writer Marv Wolfman. He had a break from DC in the 1980s, when he served as art editor for First Comics for a period of three years. He returned to DC to turn 'Green Lantern' into 'Green Lantern Corps' with Steve Englehart, with whom he also made 'Millennium' in 1988.
Staton has worked on many other DC titles, such as 'Guy Gardner', 'The Huntress', 'The New Guardians' and the 4 issue miniseries 'Superman & Bugs Bunny' (2000). Since the late 2000s he is mainly involved in drawing DC's 'Scooby Doo' title, as well as 'Femme Noir' for Ape Entertainment. He has also worked on other cartoonlike serials, such as 'Archie Super-Teens', 'Casper the Friendly Ghost' and 'Richie Rich'. As from March 2011 Staton and writer Mike Curtis succeeded Dick Locher as the new team for the 'Dick Tracy' strip for Tribune Media Services.