Jos Verdegem was a fine artist and etcher of still lifes and landscapes from Ghent. He took lessons Academy of Ghent from Georges Minne, Frits Van Den Berghe and Jean Devlin. He was a volunteer during the First World War, where he eventually joined the Section Artistique of the front painters. He spent several years in Paris during the 1920s, where he further developed his skills as a painter and etcher. He was a teacher with the Academy of Ghent between 1932 and 1944, and among his pupils were artists like Leo de Budt, Rik Clément and Antoon Mortier.
Verdegem's association with the Academy during the Second World War presumably damaged his reputation. After the liberation, Verdegem turned to comics for a short period. He was the main artist for the children's magazine Ivanov's Rakkersvriend in 1947. He drew the frontpage comic 'Mijn Reis om de Wereld', as well as the interior stories 'Zwarte Havik de sachem der Sioux' and 'Het wonderbare leven van Poesjenel'.