Against Pain is the first collection of multipage anthology pieces by Ron Rege Jr. The storytelling side of his expressive work is featured in these comic strips gathered from McSweeney's, The New York Times, Kramers Ergot, NON, Rosetta, Arthur, The Comics Journal, and Drawn & Quarterly's anthology. Suicide bombers, art appreciation, and a Lynda Barry "cover" are brought together under the theme of suffering and how people cope with it. Against Pain also includes the alt-comics zine classic Boys: a 22-page collaborative comic--considered by many to be Rege's finest work--illustrating the "lust life" of a friend in explicitly honest and hilarious detail.
"Ron Rege is one of a handful of cartoonists not only to reinvent comics to suit his own idiosyncratic impulses and inspirations, but also to imbue them with his own peculiar, ever-changing emotional energy. To me, he is unquestionably one of 'the greats.'" --Chris Ware