Antonio Amodio studied at the Faculty of Architecture for a while. He eventually went to study at the Academy of Fine Arts, where he degreed in 1991. He started his professional career working in video art. He joined the publishing house Bonelli in 1994 after meeting Gino Vercelli. He started out working on 'Legs Weaver', as well as 'La Stirpe di Elän' in Zona X. In 1998, he began working on 'Jonathan Steele'.