Piero Bernardini studied to become a railroad technician, but eventually chose an artistic career. From 1908, he worked for Passerotto, the supplement of Il Giornalino della Domenica. During World War I, he worked for La Trincea. After the War, he intensified his collaborations, and became a versatile illustrator. He also drew for Il Corriere dei Piccoli, Il Giornale dei Balilla and Gazzetta del Popolo. In the 1920s, he created several comics for Il Corrierino, such as 'Don Chisciotte Coragiosi', 'Sussi e Biribissi', 'Cimabue' and 'Mago Melino'. He continued to draw after Word War II. In 1971, he wrote his autobiography.