Fabrizio Busticchi got his degree in advertising art at the Art Institute of Monza. He began his professional career as an illustrator for Rizzoli. He did his first comics for Corrier Boy ('Edge'), Intrepido, SuperGulp! and Full. He illustrated the adventurous archeologist 'Allan Quatermain' with a script by Alfredo Castelli. He also illustrated episodes of 'Martin Mystère', before he became a staff artist on 'Mister No' (working together with Luana Paesani).