Jean-Christophe Chauzy worked for the rock music press during the 1980s. He also taught drawing classes at an Applied Arts school. He made his album debut in 1988 with 'Vengeance', which was published in the collection X by Futuropolis. By 1990, Chauzy had already finished two other albums, but these didn't appear due to the folding of the collection. They were eventually published under the title 'Novice' by PLG ten years later.
Chauzy continued to cooperate with Futuropolis during the early 1990s, creating 'Bayou Joey', 'Les Écorchés' and 'Sans Rancoeur'. From 1992, he was present in the magazine À Suivre. He cooperated with Matz on several short stories, that were collected in the album 'Peines Perdues' by Casterman. In 1993, he made 'J'ai Tué mon Prof' with Mosconi at the publisher Syros. In 1995, he published 'Parano' at Casterman and made 'Béton Armé' in À Suivre. He also contributed to the alternative comics magazine Ogoun!. Also for Casterman, he produced 'Le Peau de l'Ours' in 1998, and created 'Clara' with Denis Lapière between 1999 and 2002.
In 2000, he was present at Les Rêveurs de Runes with 'L'Âge Ingrat'. He also teamed up with the novelist Thierry Jonquet and adapted 'La Vigue' and 'La Vie de ma Mère' in 2001 and 2003. Chauzy and Jonquet subsequently cooperated on 'D.R.H.' (Casterman, 2004) and 'Du papier faisons table rase' (Casterman, 2006). With Marc Villard, he made the graphic novels 'Rouge est ma couleur' (2005) and 'La Guitare de Bo Diddley' (2009), also for Casterman. Together with Zep and Yan Lindingre, he created the humorous series 'Petite Nature' for Fluide Glacial, that has been published in books by Audie since 2007. In 2010, he started the serial 'Bonne Arrivée à Cotonou' with Anne Barrois at Dargaud.