Stéphane Collignon studied graphic arts at the EMSAT. Afterwards, he studied at the University of Saint-Denis, where he met his future fellow artists Nicolas Bournay, Fabrice Druet and Sylvain Guinebaud. After his military service, he started the series 'Lex' with writer Froideval at Glénat. He also teamed up with his university friends to start 'Requiem Tenebrae', a collective project initiated by Nicolas Bournay. With Christian Villa, he began 'Neurotrans' at Albin Michel in 2004.