Chantal De Spiegeleer was born in Kinshasa, Zaire, in 1957. From 1974, she studied arts at the Institut Saint-Luc in Brussels, where she worked in Claude Renard's Atelier R. Her first comic pages were published in Le Neuvième Rêve. In 1982, Moretti published her first album, 'Mirabelle'. Afterwards, De Spiegeleer turned to the advertising field. In 1985 she started travelling with René Sterne and she became the colorist on Sterne's 'Adler' series. Three years later, she started her own series, 'Madila', a saga set in the middle of an imaginary city. She drew four albums of the series until 1995. She and Sterne settled on the Grenadine isles. In 2004, she began the series 'Éclipse' with Jules d'Oultremont at Lombard.
She was one of several artists to make a graphic contribution to ‘Pepperland’ (1980), a collective comic book tribute to the store Pepperland, to celebrate its 10th anniversary at the time.
