Debbie Drechsler was born in Champaign, Illinois in 1953 and moved many times as a child. She studied at the Rochester Institute of Technology and started working in illustration and design. She got involved with the feminist movement and discovered Wimmin's Comix, which inspired her to try new things in her own art. In the mid-1980s, she moved to Northern California and met Richard Sala.
Her first comic came out in 1992, published in the Drawn & Quarterly magazine. In 1996, her heart-breaking graphic novel 'Daddy's Girl' was published, a shocking tale about incest, which was nominated for the Igntaz Award. She started the series 'Nowhere', which ended after five issues in 1999 and was published as a graphic novel under the title 'Summer of Love' in 2002.
Debbie Drechsler works as an illustrator and lives in Santa Rosa, California. Her work is published in several magazines and newspapers, including Yankee Magazine, San Jose State Alumni Magazine, U.S. News & World Report, Redbook, Texas Monthly, Cricket Magazine, Shape, Condé Nast Traveler, The Los Angeles Times, The Oakland Tribune, The San Francisco Chronicle, The Washington Post and publications by Avon Books, Bantam Books and Mercury Press.