Leone Frollo made his debut in 1948 with 'Sui Grandi Laghi', a series published in Risveglio. From 1958 to 1963 he worked for Fleetway in London, where he made numerous war stories. Also for the British market, Frollo created several sentimental stories with the Roy d'Ami studios.
From the late 1960s to the mid-1980s, he illustrated numerous popular series in several genres, like history, fantasy, horror, but mostly eroticism. He has cooperated on Terror and Lucifera at Ediperiodici, Biancavene and Naga at Edifumetto, as well as the magazines Skorpio and Lanciostory. From 1987 he changed his graphic style and drew 'Malicieusement Femmes', 'Mona Street' and the 'Diva' series. In 1997, Glamour publishers released Frollo's version the story of Snow-White.