Renzo Orrù showed early interest in comics. This resulted in the young Renzo following a course in drawing and illustration, held by Aurelio Galleppini in 1947. That same year, he was assigned by Milan publishers to illustrate the western story 'La Grande Corsa'. In the 1950s he illustrated for a local weekly, La Sardegna Illustrata. His first real encounter with the comics profession came in 1953, when he started working for the Genova situated publisher Giovanni de Leo. There he illustrated comics like 'Thunder Jack', 'Tom Tom', 'Maskar' and 'Ted Tuono', mostly written by De Leo. In the 1960s he also illustrated some fairytale books for De Leo.
Afterwards, the moved over to the Milanese publisher Gino Sansoni, where he took over graphically the 'Maciste' series for a while. He then moved back to Sardinia, where he started working for Il Vittorioso magazine. Here, Orrù created western stories. In the early 1970s he worked for Panini di Modena for a couple of years, illustrating several comics for Il Paladino magazine. He also took on some horror, erotic and war stories for Dardo publishers. From the 1980s, Orru has devoted himself to painting.
