Osvaldo Pérez D'Elías was born in Buenos Aires and attended the Pan-American School of Art. In 1962 he began drawing for Guilermo Divito's Rico Tipo magazine. He then worked for Tia Vicenta and created his first comics for Siete Pelos with Hector German Oesterheld. Over the years, his work has appeared in TV Guía, Goles, Gente, El Gráfico, El Satiricón and the Catalan edition of Mad. He drew 'El Mundo de Zópitas' with texts by Jorge Martinez in El Clan de Mac Perro, the 1970s supplement of Billiken magazine.
Pérez D'Elías settled in Spain in 1986, where he worked as a caricaturist for magazines like Dunia, Interviú, Hombre de Hoy and El Europeo. He has worked for ABC and Blanco y Negro for over twenty years. He was also present in the Italian magazines Playboy and Il Giovedi.