Bruno Tremulo moved to Milan after finishing his military service in 1971. Here, he studied Advertising and mad his first moves in the comics field. In early 1972, he got his first assignment of the Martini-Maffi agency of Lug publishers. It was the beginning of a longtime cooperation. Tremulo did several publications for France, like the western 'Perro e Doc', the exotic 'Borneo' and 'Magic John'. From 1979 to 1981 he worked for periodicals like Intrepedo, Il Monello and Albo Bliz, where he replaced the Spanish artist Cesar on the serial 'Anni Ruggenti' and drew 'Quelli delle Chiavi d'Oro'.
In late 1981, Tremulo started working for Corrier Boy magazine. There he illustrated 'Nat Fly', a series set in Central America. During the 1980s he illustrated numerous pockets for Edifumetto. In 1987, he left the comics field to start a career in the advertising world.