Brian Buniak was born on 14 August 1952 in New Jersey into a family of Polish descent. Graduating from the Newark School of Fine and Industrial Arts, he was a part of the underground comix scene of the 1970s, contributing to Mood Publishing's Amazing Adult Fantasies and New Paltz Comix where his 'The Sprite' (1974) was the first satire of Will Eisner's 'The Spirit'. In the late 1970s and early 1980s he turned to illustrating for Christian publishers such as Logos International (Logos Journal), Strang Publications (Charisma magazine), and Gospel Light (Sunday School publishers).
From 1982 to 1987 he and scriptwriter Marty Greim collaborated on 'Thunderbunny' stories for Charlton Comics, Apple Comics, Archie Comics, and WaRP Graphics. From 1986 to 1988 he drew some 'Mr. Monster' stories scripted by Michael T. Gilbert for Dark Horse Comics, and subsequently drew other stories for Dark Horse until 1993, and one in 2010. In 1989-90 he drew stories for Richard Corben's Fantagor Press, and also covers and stories for the Christian comics 'Aida-Zee' #1, 'Paro-Dee' #0, and 'Christian Comics & Games' #0 and #1, published by the Nate Butler Studio.
His cartoons and caricatures have appeared in The Daily News, Mad magazine, Cracked magazine, and The Limbaugh Letter. Buniak drew short stories for 'The Big Book of…' series published by DC Comics' Paradox Press imprint from 1998 to 2000. He also drew the 'Angel and the Ape' backup feature in DC's 'Joe Kubert Presents' mini-series in 2012-13. Brian Buniak has served as an instructor at the Kubert School since the late 1990s.