Born in Manhattan and raised in Brooklyn, Irwin Hasen started his cartooning career in the late 1930s, after attending the National Academy of Design and the Art Students League in New York. He first drew sports cartoons and did advertising artwork. Hasen went into comic books in 1940, working on such titles as 'The Green Hornet', 'The Fox', 'Secret Agent Z-2', 'Bob Preston, Explorer', 'Cat-Man' and 'The Flash', through the Harry "A" Chesler shop. In the same period he created the short-lived feature 'Citizen Smith, Son of the Unknown Soldier'. By 1941, Hasen went to work for Sheldon Mayer, and worked on several episodes of 'The Green Lantern for National/DC.
During his military service, he was responsible for the military paper Fort Dix Reception Center. Discharged from the army in 1946, Hasen went back to doing more comic book work. For National Periodicals, Irwin Hasen drew, among others, features like 'Johnny Thunder' and 'The Justice League of America'. He also returned to 'The Flash' and 'The Green Lantern'. He also briefly worked on a daily strip of 'The Goldbergs', based on a radio show. In the 1950s Hasen became active in the National Cartoonists Society. While on a tour in Europe, he met Gus Edson. Together, they co-wrote 'Dondi', a comic strip about an orphan boy, drawn by Hasen. The strip ran in more than 100 newspapers from 1955 to 1986. Hasen subsequently went into semi-retirement. He passed away in March 2015.