André Gaudelette began his career in the 1940s, working as an illustrator for publishers like Les Éditeurs Réunis on collections such as France d'Abord. Under the pseudonym André Joy, André Gaudelette drew the 'P'tit Joc' series. This series about a little orphan boy was written by Jean Ollivier and appeared in Vaillant from 1952 to 1957. He then briefly drew 'Jojo des Rues' for the magazine. Joy left Vaillant in 1957 to make the title comic of Lombard's Line magazine under his own name with Charles Nugue for a while.
He began a collaboration with Fleurus publishers in 1961. There, he created 'Frank et Siméon' for Coeurs Vaillants/J2 Jeunes and 'Les Enquêtes de Nicole' for Ames Vaillantes/J2 Magazine. Later on, he illustrated 'Judy' for the magazines Djinn and Triolo. He additionally drew comics for Francs-Jeux, Nade, Lisette and Amis Coop, before retiring in 1987. André Gaudelette is the father of comics artist Michel Gaudelette.