J.O. Ladrönn has done some projects for DC and Marvel in cooperation with Randy and Jean-Marc Lofficier in the mid-1990s. His first comicbook work was published in Marvel's 1997 comicbook Shadows & Light #1. That same year he also penciled 'Spider-Boy Team-Up' #1 for Amalgam Comics (a joint venture between Marvel and DC) and Moebius Comics #5 for Caliber Press. Ladrönn illustrated the first three issues of the 'Inhumans' miniseries in cooperation with Carlos Pachero at Marvel in 2000. He drew the comic 'Hip Flask', collaborating with Richard Starkings and Joe Casey. He has also drawn 'Fantasic Four', as well as several covers for DC, Dark Horse and Black Coat Press. In 2004, he did a story for Metal Hurlant with a script by Alejandro Jodorowsky ('Tears of Gold').