Carol Lay grew up in California, where she had a pretty dull and isolated childhood. In 1970, she went to the University of California in Los Angeles, where she discovered sex, drugs, Frank Zappa and 'Zap' comix. She graduated in Fine Arts and started drawing comics herself, which were published in underground comix magazines like Last Gasp and Rip Off Press. To earn a living, Carol Lay worked as an advertising illustrator and did various jobs for mainstream comic companies such as Western Publishing and DC.
She eventually quit to be able to do more of her own work. After doing five pages of comics for the LAWeekly, she decided to make her own weekly comic. This became 'Story Minute', which has become very popular since its first appearance in 1992, and is now published in Hong Kong and Japan as well as in the US. Many of the 'Story Minute' strips have been collected in the albums 'Strip Joint' and 'Joy Ride'.