Born in 1930, in South Woodford (London), Mike Noble attended the School of Art S.W. Technical College in Walthamstow in 1946. During the late 1940s, he worked in an advertising studio in Holborn. By 1949, he served National Service by illustrating armoured vehicles, in the drawing office of the 8th Royal Tank Regiment. Back in civil life, he worked in a Chelsea studio and later in Cooper Studios in Oxford Street, London, where he did magazine illustrations for Woman's Own, John Bull, Woman, Odhams and the Birmingham Weekly Post.
Noble started drawing comic books in 1953. He initially did his own strip, 'Robin', for Hulton Press. He became a freelancer in 1956 and contributed work to TV Comic, before becoming a staff artist at TV Century 21 Comics. There, he illustrated comic version of Gerry Anderson TV productions like 'Fireball XL5', 'Zero X' and 'Captain Scarlet and the Mysterons'. Noble furthermore illustrated an early 'Star Trek' strip for the Joe 90 Comic in 1970.
He eventually left TV21 and joined Look-In magazine, produced by Independent Television Publications, where he drew the 'Timeslip' comics until the late 1980s. Noble's other credits include 'Follyfoot', 'The Famous Five', 'The Tomorrow People', 'Kung Fu', 'Worzel Gummidge', 'Robin of Sherwood' and 'Space: 1999'. He retired from comics due to health reasons in the 1980s, but returned in the 1990s to draw covers and illustrations for Gerry Anderson's new 'Thunderbirds' and 'Captain Scarlet' comics.