Mark Schultz was born near Philadelphia and raised outside Pittsburgh. He got his degree in Fine Arts in 1977 and worked as a commercial illustrator until 1986. That year, he submitted his first 'Xenozoic Tale' to Death Rattle Anthology #8. A year later, Schultz had his own 'Xenozoic Tales' comic book. Marvel and Topps published spin-off series later on, both titled 'Cadillacs and Dinosaurs' and under Schultz's supervision.
As an artist, he was also working on such series as 'Predator: Hell and Hot Water', 'Johnny Quest', 'Tarzan', 'Star Wars', 'Death Rattle' and 'The Spirit'. Mark Schultz's writing credits include 'Sub-Human', 'Superman - Man of Steel', 'Predator: Hell and Hot Water', 'ALIENS', 'Flash Gordon', etc. Throughout his career, Mark Schultz has received several awards.
He was one of several veteran comics authors to contribute to Matt Groening's 'Bart Simpson Treehouse of Horror 11' (2005), along with Angelo Torres, Al Williamson, John Severin, Len Wein, Berni Wrightson, Marv Wolfman and Gene Colan.