Marc Silvestri was born in Palm Beach, Florida, and began his career pencilling titles like 'Uncanny X-Men' and 'Wolverine' for Marvel in the late 1980s and early 1990s. Silvestri, together with Todd McFarlane, Rob Liefeld, Jim Valentino, Whilce Portacio, Erik Larsen and Jim Lee formed Image Comics in 1992.
From then on, he published his work under the Top Cow imprint, including the series 'Cyberforce', 'Witchblade', 'Weapon Zero', 'The Darkness' and 'Hunter-Killer'. In 2004, Silvestri returned to Marvel and 'X-Men' for several issues. He eventually went back to Top Cow and launched titles like 'Hunter-Killer'. In 2007, he did the 'X-Men: Messiah Complex' one-shot for Marvel.