Bernard Vrancken showed an early talent for drawing. At age fifteen, he was one of the winners of a contest organized by the Academy of Fine Arts. At age 16, he published his first historical comic stories in Tintin magazine. While studying architecture at Saint-Luc, he was a pupil of Eddy Paape at the Saint-Gilles Academy. He began his longtime association with Stephen Desberg shortly afterwards.
Vrancken and Desberg made about a dozen short stories for À Suivre, before embarking upon the romantic saga 'Le Sang Noir' for Le Lombard between 1996 and 1998. They subsequently started their best-known work, the ongoing political-financial thriller 'I.R.$.' in Lombard's Troisième Vague collection in 1999. The duo added the heroic fantasy series 'H.Ell' to their resume in 2013.