Enrique Cerdán's first work was a shortlived daily comic strip in the newspaper Levante. This was a western and appeared in 1953. Since the beginning of the 1960s, he was an artist for the publishing house Valenciana, mostly for the weekly magazines Jaimito and Pumby. For Pumby, he created the adventures of the little indian 'Plumita' (with a strong resemblance to Disney's 'Hiawatha') Other series he wrote and drew for Valenciana were: 'El Grumete Timoteo', 'La Tripulación del Barquito Cascarón' and 'El Hotelito Calamar'. Cerdán was working for this publisher until its disappearance in the 1980s.
Through Bardon Art and other international agencies, Cerdán also worked for different countries, such as Denmark, Germany, the UK, Holland and Italy. This was much better paid than the work he did for his own country. For foreign publishers, he dealt with such famous Disney's characters as 'Donald Duck' and 'The Big Bad Wolf'.
For the German market, he contributed to Fix und Foxi and Yps, and for Holland, he drew for 'Dr Snuggles'. Enrique Cerdán also appeared in supplements of newspapers (Lapicerín, La Hora del Recreo, Jipipa). Besides he worked for Spanish publishers other than Valenciana, such as Bruguera, Ortells, Iru, and Ediciones B.