Robert C. Moore was born in California in 1920. He briefly attended art classes at the Chouinard Institute in Los Angeles, and made his debut at the animation studios of Walter Lantz. Moore's father was a violinist with the Los Angeles Philharmonic Orchestra, and had played on several Disney shorts, including 'Steamboat Willie' and 'Plane Crazy'. In 1940, Bob Moore also got a chance to work at the Disney Studios, and became the assistant of Walt Kelly on animating 'Fantasia' and 'Dumbo'. Moore subsequently joined the Story Department, working as a gag man on 'The Reluctant Dragon' and 'The Three Caballeros'.
Moore also worked on the several propaganda films the studios made for the American Army during World War II. In late 1948, he went to work for the Publicity Art Department, where he did artwork for posters, books and other promotional material under guidance of Hank Porter. When Porter left the department in 1950, Moore became art director. He remained in this position until his retirement in 1983.
As for his comics work, Bob Moore had already contributed to Lev Gleason comic books in 1947-48. Between 1950 and 1952, Moore also drew for the Disney comic books published by Dell/Western. He illustrated mainly 'Donald Duck' stories for Walt Disney's Christmas Parade and Four Color Comics, but he has also done some work on 'Grandma Duck' and 'Little Bad Wolf'. In addition, Moore drew for the Little Golden Books series in 1952-53.