Bill Perry was born as William Miles Perry in Chicago in 1905. He began his career as a shipping clerk for the Chicago Tribune Syndicate, and took art classes in the evenings. He was hired as an assistant on 'Harold Teen' by Carl Ed, and started assisting Frank King on 'Gasoline Alley' in 1925. Between 1947 and 1950, Bill Perry had his own Sunday page comic, 'Ned Handy'. He took over the 'Gasoline Alley' Sunday page on 29 April 1951 and continued it until 1975. He was succeeded by Bob Zschiesche until 1979, when dailies artist Dick Moores assumed art and writing duties on the Sunday page as well.