Born in Hollywood, California, Keith Tucker started out doing murals in the 1970s. In the 1980s, he made name as a Hollywood animator and storyboard artist, working for Steven Spielberg, Disney, Warner Brothers and Marvel cartoons. Among the shows he worked on are 'Pinky & the Brain', 'Looney Tunes', 'Animaniacs', 'X-Men' and 'Spider-Man'.
As a comic artist, he did script and art on '3-D Alien Terror' for Eclipse in the mid-1980s. He did covers for Disney magazines like Chip 'n' Dale Rescue Rangers, Goofy Adventures and Roger Rabbit in 1990-91. He also worked on Looney Tunes comics for Warner Brothers (DC), and on historical graphic novels about Alexander Graham Bell, Philo Farnsworth, the Apollo 13, George Washington Carver and others, for Capstone Press. Nowadays, he self-syndicates his weekly cartoon 'What Now Toons'.