Otto Soglow, born and raised in New York City, was inspired by early comic artists like Winsor McCay, George McManus and George Herriman. His first illustration was published in 1919, in Cartoons magazine. In the mid-1920s his professional career took flight, with publications in College Humor, Lariat, Life and Judge. He was a member of the New Yorker crew, together with Harold Ross, S.J. Perelman, James Thurber, E.B. White and others, who greatly contributed to the magazine's popularity by thinking up wacky jokes.
One of Soglow's drawings, depicting merely a city street with an open manhole, ran dozens of times with different gags. One of Soglow's characters, The Little King, became famous, attracting the attention of newspaper tycoon William Randolph Hearst.
From 1934 onward, 'The Little King' ran as a newspaper strip, gaining popularity in the U.S. and eventually appearing all over the world. In Europe, Willy Vandersteen was one of Soglow's great admirers. Soglow was a co-founder of the National Cartoonists Society, and continued to draw The Little King until his death in 1975.