Themo Lobos already drew cartoons when he was still a child. By the age of 18, he saw his first work published in the La Nación newspaper. He studied Applied Arts, and created his first characters, 'Ferrilo el Autómata' and 'Homero el Piloto' afterwards. During the 1950s, he was a regular contributor to El Peneca, and in the following decades, he published in Barrabases and Mampato. He also occasionally drew for Cosquillas and El Pingüino. He is best known for his rendition of 'Mampato' in the 1970s, a character created by Eduardo Armstrong and Oscar Vega in 1968, and published in its own periodical. A motion picture based on one of Mampato's adventures was released in 2002. Themo Lobos is furthermore the creator of characters like 'Máximo Chambónez', 'Nick Obre', 'Alaraco', 'Agua de Boldo' and 'Dolchevita'.