Erik Meynen was born in Kapellen. When he was 9, he drew his first comic series, 'Dave de Cowboy'. Contrary to most children of his age he did have the patience and perseverance to make 14 comic book albums about this character. He studied at the Royal Academy of Fine Arts in Ghent. He mostly grew up with Belgian comic artists like Hergé, Willy Vandersteen, Marc Sleen, Jef Nys and André Franquin as graphical inspirations.
In 1978 Meynen had a summer job drawings backgrounds for Merho's comic series 'De Kiekeboes', more specifically the album 'Kiekeboe in Carré', which is set in Amsterdam. A year later Meynen made his debut as cartoonist in Knack. Together with scriptwriter Pjotr (Piet de Rycker) he created the cult comic series 'Tommy Gun & Marion Lee' (1980), which appeared in publications like Robbedoes and was collected in a book by Magic Strip in 1983. They also made 'De Terugkeer van Roxane', that was published in book format by Paul Rijperman in 1983. Both men also made a photo comic for comic magazine Spetters, using the pen names "Protter & Zweynen". In 1989 Meynen also illustrated a few stories by Kamagurka, which appeared in the comics series 'Lava'.
In 1988 Meynen met Belgian cult novelist Herman Brusselmans, who'd become one of his best friends and most vocal admirers. Together they made a detective parody series, 'Inspecteur Bob Lost Het Bijna Op' (1988), written in Brusselmans' characteristic vulgar-ironic style. It was published in Panorama/De Post. One episode, where the assertive inspector meets Belgian king Boudewijn/Baudouin, also livened up Johan Anthierens' anti-royalist book 'Brief Aan Een Postzegel' (1990). Another collaborative effort with Brusselmans and Geert Clarisse was the didactic album 'Een Bos op Zoek naar Bomen' (1988). This book was published in celebration of the European Year of Living Environment.
Another controversial man with whom Meynen worked together was the infamous stock market guru and politician Jean-Pierre Van Rossem, who was arrested for fiscal fraud in 1990. A colourful media celebrity, Van Rossem had already inspired cameos in Marc Sleen's 'Nero' series (in the 1990 albums 'De Man van Europa' and 'Nerorock') before Meynen got the idea to make an actual comic strip about him. Despite being in jail at the time, Van Rossem wrote the scripts himself. The satirical series was pre-published in Panorama/De Post and later distributed by publishing company Loempia. Due to low sales only two albums were made.
Since 1990, Meynen is best known as a political cartoonist, though he mostly abandoned the one-panel format in favor of actual gag comics. His work is published in Panorama/De Post (later P-Magazine), De Morgen and Het Laatste Nieuws. Focusing on Belgian politics, Meynen reduces politicians into literal comic book characters, complete with all the slapstick and mayhem found in regular gag strips. He often refers to topical events, but just on the level of what the average man in the street might know. He refuses to do any deeper research than that. This allows him to focus more on comical ideas, such as giving high profile politicians a talking animal as personal advisor. While not always that flattering to them, many Flemish politicians have said that they enjoy his cartoons, including Bart Somers, Steve Stevaert, Freya Van den Bossche and former prime ministers Jean-Luc Dehaene, Guy Verhofstadt and Yves Leterme. Dehaene in particular felt that Meynen's caricatures "contained more truth than any newspaper article." Meynen compiles his best gags usually after a government term is finished. So far he published the books: 'De Jaren van Dehaene' (1999), 'De Plannen van Verhofstadt' (2003), 'Paniek in de Politiek' (2006) and 'Het Lijden van Leterme' (2009).
As a comics writer, Meynen cooperated with Dirk Stallaert on several comics for Unizo and De Standaard, including 'De Mysterieuze Klant' and 'De Neuzen van Sniezo'. When asked by De Standaard to make a comic strip about typical Belgian phenomena in the essay 'België Blootgelegd' ('Belgium Exposed'), Meynen and Stallaert made a story about the French fries store of Jan Spier, a character from Marc Sleen's series 'Nero'. The two detectives in this strip, 'Pakkeman & Poulet', proved to be such fun characters that they became a monthly riddle comic, published in the civil servant magazine Fedra.
In 1999 Meynen began working for Studio Vandersteen as provider of ideas for the comic strip 'Suske en Wiske'. Together with Marc Verhaegen he was involved with the modernization of the series, which caused a lot of commotion. One of the most controversial aspects was changing the outfits Suske and Wiske wore for more than 50 years. After a public backlash they were forced to hark this idea back a little. Several albums were criticized for deriving too much from the original spirit of the series. 'De Koeiencommissie' (1999), for instance, with its countless rapidly dated allusions to Belgian politics in the late 1990s, felt closer to Meynen's political cartoons than a children's comic.
In 1999, he won the Bronzen Adhemar, the official Flemish Community Cultural Prize for Comics.