Gilbert Shelton's talents surfaced early with his silly superhero spoof 'Wonder Warthog' which was published in a campus magazine in 1959 (Ranger). In 1969, together he introduced 'The Fabulous Furry Freak Brothers' - with Phineas, Freewheelin' Franklin and Fat Freddy. He was later joined on this comic by Dave Sheridan, and after Sheridan's death Paul Mavrides worked on it as well.
Through the years, Shelton created several comic books, filled with riotous slapstick, full-speed action and extremely funny characters, all pleasantly mingled in his extraordinary limber drawing style. He earned his big money by selling the film rights to his characters, although this movie has never been made. Gilbert Shelton is considered one of the most well-known underground cartoonists. Recently, he has been working in Paris, together with Pic, on the Rock & Roll comic 'Not Quite Dead', about the world's most famous band that never made a CD.
Together with 20 other comic artists (Zep, Ptiluc, Frank Margerin, Yslaire, Cosey, Philippe Vuillemin, Milo Manara, Loustal, Max Cabanes, Dupuy & Berberian, François Boucq, Gérald Poussin, Thomas Ott, Frank Pé, Frank Le Gall, Riff Reb's, Eric Buche, Enrico Marini and Valott) he illustrated a record single for the project '20 Vraies Fausses Pochettes De Disque Par 20 Vrais Dessinateurs de BD' (1995). Shelton chose for a song by Clarence "Gatemouth" Brown.